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Shōko, una niña con discapacidad auditiva, es víctima de acoso en su escuela, siendo Shōya su principal agresor. Cuando ella se cambia de colegio, él sufre el rechazo de sus compañeros y queda aislado. Años después, intenta enmendar su error y hacer las paces con Shōko.

Operating out of the movie capital "Nyallywood," Pompo has been shooting one B-grade entertainment flick after another that anyone would enjoy. One day, Pompo's "movie buff" assistant Gene spots a new script written by Pompo and is moved by its exquisite story. In a fit of passion, he proclaims, "I want to see this as a finished work in theaters as soon as possible!" However, Pompo tells him, "So you shoot this film." Thus, Gene takes on his first directing gig. Meanwhile, Natalie, an ordinary girl who just arrived in town with movie actress dreams, has been discovered by Pompo...

Arata Kaizaki (27) quit the job he landed after graduation in only three months. His life did not go well after that. Now his parents are threatening to stop sending money, and want him to come back to the country. He has no friend or girlfriend to share his troubles with...as he hits rock bottom a strange man named Ryou Yoake appears. He invites Arata to join a societal rehabilitation program for NEETs called ReLife. This program uses a mysterious drug to make him look younger, and sends him back to high school for a year...

Inspired by a small-statured pro volleyball player, Hinata creates a volleyball team in his last year of middle school. Unfortunately the team is matched up against the "King of the Court" Tobio Kageyama’s team in their first tournament and inevitably lose. After the crushing defeat, Hinata vows to surpass Kageyama After entering high school, Hinata joins the volleyball team only to find that Tobio has also joined.

At the end of her first year of high school, Futaba Yoshioka suddenly has a chance encounter with her first love, Kou Tanaka. Three years ago, he transferred schools before she was able to say how she felt about him. After meeting each other again, Futaba realizes that he has gone through many changes. He acts more cool and even had his last name changed to Mabuchi. Gradually the two rekindle their love while piecing together what had happened in the time that they were apart.

Set six years prior to the events of Barakamon, detailing the life of Seishuu Handa as a high school student—and a very interesting life it is. In Handa-kun, Seishuu Handa is admired by his peers as a calligraphy genius and given the utmost respect, but Handa-kun himself is under the mistaken impression that the deference and attention he receives from the other students is actually bullying. Handa just wants to live a quiet life, but hilarity ensues as one character after another challenges his position as the school idol, and somehow comes away as a fan all while Handa is horrified and clueless.

High school student Chiyo Sakura has a crush on schoolmate Umetarō Nozaki, but when she confesses her love to him, he mistakes her for a fan and gives her an autograph. When she says that she always wants to be with him, he invites her to his house and has her help on some drawings. Chiyo discovers that Nozaki is actually a renowned shōjo manga artist named Sakiko Yumeno. She then agrees to be his assistant in order to get closer to him. As they work on his manga Let's Fall in Love (恋しよっ), they encounter other schoolmates who assist them or serve as inspirations for characters in the stories.

Love is unusual for Koizumi Risa and Ootani Atsushi, who are both striving to find their ideal partner in high school—172 cm tall Koizumi is much taller than the average girl, and Ootani is much shorter than the average guy at 156 cm.

Tomboy Tomo couldn't have picked a more awkward high school crush 'cause it’s on her childhood friend, Junichiro, but he only sees her as one of the guys. Despite her pretty looks and signals, nothing gets through to this meathead! Will Junichiro ever realize Tomo's into him and see her for the cutesy girl she actually is?!

To trust is to set yourself up for failure. That’s the lesson Mei Tachibana learned when her heart was broken. She found a solution: never make any more friends. It’s not as easy as it sounds, but it works for Mei. At least it did until handsome and charming Yamato Kurosawa showed up to complicate everything. Mei’s not looking for a white knight. So why did he have to kiss her and ruin everything? Between heartbeats and behind trembling lips the specter of betrayals past, future, and present haunt them both in Say "I Love You"!

At a high school full of unique characters, Tadano helps his shy and unsociable classmate Komi reach her goal of making friends with 100 people.

Tsutsui Hikari (a.k.a "Tsuttsun") is a high school student who is content with his virtual life of anime and video games. One day, he gets stuck cleaning the pool with Iroha, a real live girl who is stylish, sassy and known to be easy with boys ... and she aggressively approaches him! Tsuttsun, who has few friends and lives in his own world, finds himself smitten by the confident and wild Iroha ... and his whole world is turned upside down!! It's the awkward and pure love story of a boy who experiences relationship for the first time.

The girls in a high school literature club do a little icebreaker to get to know each other: answering the question, "What's one thing you want to do before you die?" One of the girls blurts out, "Sex." Little do they know, the whirlwind unleashed by that word pushes each of these girls, with different backgrounds and personalities, onto their own clumsy, funny, painful, and emotional paths toward adulthood.

Suzuki's a high school girl in love, but the guy she's fallen for is nothing like her! While she's cheerful, outgoing, and always trying to fit in, her classmate Yusuke Tani is stoic, quiet, and doesn't seem to care what people think of him. Will Suzuki be able to overcome her anxieties and ask him out, or will she discover that opposites really don't attract?

Menacing in appearance but gentle at heart, second year high school student Ryuuji forms an unlikely friendship with classmate Taiga, a tiny girl with a sharp tongue and a tough attitude.

In Tokyo, a weak, unassertive boy named Sena Kobayakawa enters the high school of his choice, Deimon Private Senior High School. Sena's only remarkable physical abilities are his running speed and agility, which are noted by the school's American football team captain Yoichi Hiruma. Hiruma forces Sena to join the Deimon Devil Bats football team as its running back. To protect his identity from other teams who want to recruit him, Sena is forced to publicly assume the role of the team secretary and enter the field under the pseudonym of "Eyeshield 21" wearing a helmet with an eyeshield to hide his features.

Violent delinquent Oga encounters a baby one day, which crawls onto his back and immediately forms an attachment to him. Though he doesn't know it yet, this baby is named Kaiser de Emperana Beelzebub IV, or "Baby Beel" for short—the son of the Demon Lord!

When the intimidating Rintaro meets the open-minded Kaoruko, the unlikely duo grows closer. The issue? Their neighboring high schools hate each other.

Sakamoto is not a normal high schooler. He’s smart, he’s dashing, he’s popular with girls. Much to the dislike of the male population of his school, who tries every trick in the book to mess Sakamoto up. But in the end, Sakamoto comes out of every trap with style and makes himself look cooler. Does he do this for popularity? Is this just who he is? No one really knows, but haven’t you heard? He’s Sakamoto!

Bored with life, popular high schooler Yatora Yaguchi jumps into the beautiful yet unrelenting world of art after finding inspiration in a painting.