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Cuatro años después de que el enfermero Greg (alias Gaylord) Focker, durante un fin de semana en casa de sus suegros, se las ingeniara para perder el equipaje, provocar un incendio y pintar a un gato, por fin, ha conseguido ganarse la confianza de su suegro y todo son planes de boda. Sólo queda un pequeño escollo que superar: los futuros consuegros deben pasar un fin de semana juntos para conocerse mejor y, sobre todo, para que Jack, el padre de la novia, pueda estudiar a los padres de Greg. Todo parece ir viento en popa hasta que Jack descubre que los padres de Greg (abogado y médico respectivamente) son demasiado liberales: él cuida de la casa y ella es una terapeuta sexual de la tercera edad.

Ray Barone is a successful sportswriter living on Long Island with his wife Debra, daughter Ally, and twin sons, Geoffrey and Michael. Ray's meddling parents, Frank and Marie, and brother, Robert, live directly across the street.

Greg Focker es un enfermero algo patoso que, tras anunciar su compromiso con novia Pam, tiene que pasar unos días con los padres de ella, para conocerles. Su encuentro inicial no será muy afortunado, en especial por las suspicacias que Greg levanta en el estricto padre de la novia, un padre protector exagente de la CIA al que es muy difícil impresionar. Desde el principio, Jim rechaza por completo a Greg, pero a medida que lo conoce mejor, su rechazo se convierte en absoluto desprecio, y se encarga de convertirse en la peor pesadilla de este hombre que, a pesar de amar a su novia y querer dar una buena primera impresión, cada vez se hunde más en el lodo de su propia ineptitud, y deberá luchar mucho para poder cambiar la pésima opinión que tienen de él los parientes de su novia.

The Pritchett-Dunphy-Tucker clan is a wonderfully large and blended family. They give us an honest and often hilarious look into the sometimes warm, sometimes twisted, embrace of the modern family.

Jim is the typical all-American guy — a macho "everyman" — with a soft spot for his beautiful wife and children. Jim's boyish bravado and humorous antics keep a certain level of turmoil in their home, but there's never a doubt that this "opposites attract" couple are in their marriage for keeps!

The daily trials and tribulations of handyman Tim Taylor, a TV show host raising three boys with help from his loyal co-host, domineering wife, and unseen neighbor.

Michael Kyle is a loving husband and modern-day patriarch who rules his household with a unique and distinct parenting style. As he teaches his three children some of life's lessons, he does so with his own brand of humor.

The bizarre adventures of Cleveland Brown and his family.

After shielding himself and his daughter from his family for over a decade, Malcolm is dragged back into their orbit when Hal and Lois demand his presence at their 40th anniversary party.

Follow the Murphy family back to the 1970s, when kids roamed wild, beer flowed freely and nothing came between a man and his TV.

The daily mishaps of a married woman and her semi-dysfunctional family and their attempts to survive life in general in the city of Orson, Indiana.

Life’s good for deliveryman Doug Heffernan, until his newly widowed father-in-law, Arthur, moves in with him and his wife Carrie. Doug is no longer the king of his domain, and instead of having a big screen television in his recently renovated basement, he now has a crazy old man.

Elegant, proper Grace and freewheeling, eccentric Frankie are a pair of frenemies whose lives are turned upside down - and permanently intertwined - when their husbands leave them for each other. Together, they must face starting over in their 70s in a 21st century world.

Before there were parenting blogs, trophies for showing up, and peanut allergies, there was a simpler time called the '80s. For geeky 11-year old Adam these were his wonder years and he faced them armed with a video camera to capture all the crazy. The Goldbergs are a loving family like any other, just with a lot more yelling.

A married father of three tries to maintain his manliness in a world increasingly dominated by women.

Margaret es una poderosa y estricta editora de gran éxito de Nueva York que, por un problema con su visado, de repente se enfrenta a ser deportada a Canadá, su país de origen. Para evitarlo y poder mantener su visa en Estados Unidos, la astuta ejecutiva declara que está comprometida con su joven asistente Andrew, al que lleva torturando durante años. Andrew acepta participar en la farsa, pero con algunas condiciones. La "pareja" se dirige entonces a Alaska a conocer la peculiar familia de él, y la ejecutiva de ciudad, acostumbrada a tener todo bajo control, se encuentra inmersa en situaciones surrealistas que escapan a cualquier lógica conocida. Con planes de boda en camino y un agente de inmigración tras sus pasos, Margaret y Andrew se comprometen a seguir con el plan previsto pese a las consecuencias.

A hedonistic jingle writer's free-wheeling life comes to an abrupt halt when his brother and 10-year-old nephew move into his beach-front house.

Al Bundy is an unsuccessful middle aged shoe salesman with a miserable life and an equally dysfunctional family. He hates his job, his wife is lazy, his son is dysfunctional (especially with women), and his daughter is dim-witted and promiscuous.

Searching for a safer habitat, the prehistoric Crood family discovers an idyllic, walled-in paradise that meets all of its needs. Unfortunately, they must also learn to live with the Bettermans -- a family that's a couple of steps above the Croods on the evolutionary ladder. As tensions between the new neighbors start to rise, a new threat soon propels both clans on an epic adventure that forces them to embrace their differences, draw strength from one another, and survive together.

A satirical inversion of the ideal of the perfect American nuclear family, they are an eccentric wealthy family who delight in everything grotesque and macabre, and are never really aware that people find them bizarre or frightening. In fact, they themselves are often terrified by "normal" people.