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High school student Chiyo Sakura has a crush on schoolmate Umetarō Nozaki, but when she confesses her love to him, he mistakes her for a fan and gives her an autograph. When she says that she always wants to be with him, he invites her to his house and has her help on some drawings. Chiyo discovers that Nozaki is actually a renowned shōjo manga artist named Sakiko Yumeno. She then agrees to be his assistant in order to get closer to him. As they work on his manga Let's Fall in Love (恋しよっ), they encounter other schoolmates who assist them or serve as inspirations for characters in the stories.

Tomboy Tomo couldn't have picked a more awkward high school crush 'cause it’s on her childhood friend, Junichiro, but he only sees her as one of the guys. Despite her pretty looks and signals, nothing gets through to this meathead! Will Junichiro ever realize Tomo's into him and see her for the cutesy girl she actually is?!

In Tokyo, a weak, unassertive boy named Sena Kobayakawa enters the high school of his choice, Deimon Private Senior High School. Sena's only remarkable physical abilities are his running speed and agility, which are noted by the school's American football team captain Yoichi Hiruma. Hiruma forces Sena to join the Deimon Devil Bats football team as its running back. To protect his identity from other teams who want to recruit him, Sena is forced to publicly assume the role of the team secretary and enter the field under the pseudonym of "Eyeshield 21" wearing a helmet with an eyeshield to hide his features.

Inspired by a small-statured pro volleyball player, Hinata creates a volleyball team in his last year of middle school. Unfortunately the team is matched up against the "King of the Court" Tobio Kageyama’s team in their first tournament and inevitably lose. After the crushing defeat, Hinata vows to surpass Kageyama After entering high school, Hinata joins the volleyball team only to find that Tobio has also joined.

In the story, Kagami Taiga has just enrolled into Seirin High School when he meets Kuroko Tetsuya of the school's basketball team. Kuroko happens to be the shadowy sixth member of the legendary Generation of Miracles basketball team. Together, Kagami and Kuroko aim to take their team to the inter-high school championship - against Kuroko's former teammates.

Shohoku's “speedster” and point guard, Ryota Miyagi, always plays with brains and lightning speed, running circles around his opponents while feigning composure. In his second year of high school, Ryota plays with the Shohoku High School basketball team along with Sakuragi, Rukawa, Akagi, and Mitsui as they take the stage at the Inter-High School National Championship. And now, they are on the brink of challenging the reigning champions, Sannoh Kogyo High School.

Suzuki's a high school girl in love, but the guy she's fallen for is nothing like her! While she's cheerful, outgoing, and always trying to fit in, her classmate Yusuke Tani is stoic, quiet, and doesn't seem to care what people think of him. Will Suzuki be able to overcome her anxieties and ask him out, or will she discover that opposites really don't attract?

Taiki Inomata loves badminton, but he has a long way to go before he can reach nationals. When Taiki sees upperclassman Chinatsu Kano practicing her heart out on the girls’ basketball team, he falls for her hard. After an unexpected turn of events brings the two closer together, sports might not be the first thing on their minds anymore!

Considered a genius due to having the highest grades in the country, Miyuki Shirogane leads the prestigious Shuchiin Academy's student council as its president, working alongside the beautiful and wealthy vice president Kaguya Shinomiya. The two are often regarded as the perfect couple by students despite them not being in any sort of romantic relationship.

Shoyo Hinata joins Karasuno High's volleyball club to be like his idol, a former Karasuno player known as the 'Little Giant'. But Hinata soon learns that he must team up with his middle school nemesis, Tobio Kageyama. Their clashing styles form a surprising weapon, but can their newfound teamwork defeat their rival Nekoma High in the highly anticipated 'Dumpster Battle', the long awaited ultimate showdown between two opposing underdog teams?

Follow the adventures of three ordinary girls as they make life’s awkward moments a thousand times worse. Along with a colorful bunch of classmates, they learn their most important lessons the hard way. Meanwhile down the street, a pocket-sized professor makes life difficult for a robot who just wants to be normal. But normal is the last thing you can expect in a town where salmon falls from the sky. In fact, the only thing you can count on is your friends, but even they are totally weird.

At the end of her first year of high school, Futaba Yoshioka suddenly has a chance encounter with her first love, Kou Tanaka. Three years ago, he transferred schools before she was able to say how she felt about him. After meeting each other again, Futaba realizes that he has gone through many changes. He acts more cool and even had his last name changed to Mabuchi. Gradually the two rekindle their love while piecing together what had happened in the time that they were apart.

The story revolves around Haruka Nanase, a boy who has always loved to be immersed in water, and to swim in it. Before graduating from elementary school, he participated in a swimming tournament along with his fellow swimming club members, Makoto Tachibana, Nagisa Hazuki, and Rin Matsuoka. After achieving victory, each of the boys went their separate ways. Time passed, and in the middle of their uneventful high school lives Rin appears and challenges Haruka to a match, showing Haruka his overwhelming power. Not wanting it to end like this, Haruka, gathers together Makoto and Nagisa once again and brings a new member named Rei Ryugazaki to create the Iwatobi High School Swimming Club in order to defeat Rin.

The students of Class 3-E have a mission: kill their teacher before graduation. He has already destroyed the moon, and has promised to destroy the Earth if he can not be killed within a year. But how can this class of misfits kill a tentacled monster, capable of reaching Mach 20 speed, who may be the best teacher any of them have ever had?

Yeah, Kenichi’s a total wimp. He’s always getting picked on and doesn’t have a lot of friends to stick up for him. The guy needs motivation if he hopes to graduate in one piece. Well, Miu’s the perfect motivation. She’s hot, she accepts him, and she just so happens to live at a dojo with six martial arts masters. You could say fate has led Kenichi to their door, or you could say he was just following the hottie. Either way, he’s about to get whipped into serious shape. If he can survive some hard-core training, he might survive another day at school. He might even score with Miu. Yeah, you could call Kenichi a wimp. But let’s go with underdog instead.

Hitori Gotoh, a shy, awkward, and lonely high school student dreams of being in a band despite her doubts and worries, but when she is recruited to be the guitarist of a group looking to make it big, she realises her dream may be able to be fulfilled and come true.

A secret life is the one thing they have in common. At school, Hori is a prim and perfect social butterfly, but the truth is she's a brash homebody. Meanwhile, under a gloomy facade, Miyamura hides a gentle heart, along with piercings and tattoos. In a chance meeting, they both reveal a side they've never shown. Could this blossom into something new?

Menacing in appearance but gentle at heart, second year high school student Ryuuji forms an unlikely friendship with classmate Taiga, a tiny girl with a sharp tongue and a tough attitude.

At a high school full of unique characters, Tadano helps his shy and unsociable classmate Komi reach her goal of making friends with 100 people.

Arata Kaizaki (27) quit the job he landed after graduation in only three months. His life did not go well after that. Now his parents are threatening to stop sending money, and want him to come back to the country. He has no friend or girlfriend to share his troubles with...as he hits rock bottom a strange man named Ryou Yoake appears. He invites Arata to join a societal rehabilitation program for NEETs called ReLife. This program uses a mysterious drug to make him look younger, and sends him back to high school for a year...